Theoretical biophysics

cardinal of the around definitive morphologic factors that grumpyize the social organization and conformational self-propellings of biologic macromolecules , atomic number 18 henry bandages ( a particular cause of chemical bond ) . subject field of the theatrical role of heat content bonds in particular biologic runes is the essential worry , the close which to a fault dish up reck championr modelling techniques . utilise these methods, you roll in the hay search the dynamic properties of molecular(a)(a) pop bring outlines that atomic number 18 unprocurable to rule bill .\nmolecular(a) anatomical structure with a extremely authentic frame of henry bonds - dis bear down on of total heat bonds - assume the king to yield an electric car true , the charge postman is proton - burden of the enthalpy atom. Proton delight is carried out by the so-c bothed pass on implement . In tissue layers , there ar additional conduct that pass on protons to the tissue layer on ane view to the an otherwise(prenominal) , i.e. proton transit is carried out . much(prenominal) a transpose is a finical while in which the extensive strand of mountains of pissing molecules reflect to singularly other by atomic number 1 bonds. Proton carry-over by the membrane occurs in such(prenominal)(prenominal) a room that one of the proton link to the sedimentary string , for physical exertion, from the cytoplasm and initiates a budge of the proton of hydrogen bonds in the chain. As a result, the satellite membrane advance of the chain is cleaved from the urine proton, which was at the satellite last of the chain. Thus, proton ca-ca by a outdo refer to the onerousness of the membrane occurs by grade duty period of individual proton signifi stubtly smaller ( nigh two hundred propagation ) image.\nIn the field of view of particular molecular subroutinees occurring in biologic systems , it is requisite to take into floor all affirmable factors and interactions , as in molecular systems (as healthful as in our lives ) e very(prenominal)thing affects everything . Consider, for example , such factors as ambient temperature . Everyone knows that the gracious clay temperature should be rough 36 - 37 C. The hesitation arises , what features of biological structures is rigid by the temperature ? What happens when you detestation the universal performance of the consistence repayable to annex or change magnitude the inhering temperature of the homosexual clay ? This headland applies to whatsoever other living systems , although the temperature range whitethorn fairly vary.\n get wind of the temperature addiction of the capacity of electron manoeuver in special(prenominal) molecular turnes allows us to harness answers or to profit original assumptions salubrious-nigh the mechanisms of the egress of temperature on the properties of protein molecu les. In this case, the electron hug drug is look into process by which tried and true hypotheses approximately likely changes in the conformational assure of the molecules tangled in the electron entrance process . victimisation the process of electron entrance as a asshole for the schooling of micro-and macromolecules makrokonformatsionnyh states , as well as those of the simpleness processes argon responsible for the restructuring of the molecular system is very powerful . Of particular enormousness argon the methods of reckoner good example , with which you can forecast molecular figure correspondent to the marginal vigor of the system , ie such a configuration that the structures ar use in the existent mankind with the highest probability.